How whole genome doubling helps cancer
A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils. The solution is chromatin: a complex of DNA wrapped around proteins called histones. In the 3D space,…
Breakthrough drug combination for Cystic Fibrosis
Patients with cystic fibrosis (CF) face difficulty breathing and a decline in lung function and are at risk of early death. CF is an inherited condition that results in thick mucus build-up, persistent infection and inflammation in the lungs. Medical…
New treatment for Pancreatic Cancer using miRNA therapy
SiSaf in collaboration with the University of Leipzig has developed Bio-Courier targeted micro interfering RNAs (miRNA therapy) in order to treat cancer, especially pancreatic cancer. The agreement of SiSaf with Leipzig university consists of, SiSaf’s work in RNA delivery with…
A new breakthrough treatment for autoimmune diseases
Scientists in Japan have revealed a chemical compound that could be used for the treatment of various autoimmune diseases like multiple sclerosis and rheumatoid arthritis. These diseases occur when the body’s immune response goes wiry. The immune system, which normally…
Digital twins explain a path to Personalized Inflammatory Disease Treatment
Inflammatory disease is when the immune system attacks the body’s own cells or tissues which results in causing inflammation. Rheumatoid arthritis, Crohn’s disease, and ulcerative colitis are some examples of inflammatory diseases having very complex disease-causing mechanisms and which can…
A breakthrough fluorescence recognition method for detecting D-glucose
Cyclodextrin and monoboronic acid-based receptor complexes show excellent D-glucose chiral selectivity ,paving the way for improved diabetes diagnostics Diabetes mellitus, simply called diabetes, is a metabolic disorder characterized by the presence of abnormally high concentrations of glucose in blood. Existing…
A new surprising function of Telomere discovered
Telomeres have been a pandora box of discovery when it comes to understanding their functions. Telomeres are known for their simplicity, making it really difficult to digest the fact that they can also produce proteins. While there is very less…
Pfizer and GSK Head on Fight for First FDA-Approved RSV Vaccine
The two leading companies in vaccine production are almost at the finish line for the world’s first adult RSV vaccine. The FDA’s approval decision is expected in May 2023. Pfizer announced that the FDA’s Vaccines and Related Biological Products Advisory…
Allergic Asthma is driven by Nerve and Immune cells
Allergic asthma is a chronic inflammatory condition in which your lungs become inflamed and the airways you breathe through tighten when you inhale any kind of allergen. It is the most common type of asthma. About 90% of kids with…
Lab grown blood stem cells can save lives?
A group of scientists at the University of Tsukuba have been successful at creating novel culture system that can pave path for ex-vivo expansion of Hematopoietic Stem Cells (HSC). Generally, HSCs are immature blood cells which when triggered can mature…