Fixed vial sizes for controversial Alzheimer’s drug could waste $605 million in Medicare spending each year
Medicare could waste up to $605 million per year on the controversial Alzheimer’s drug aducanumab if it is eventually approved for widespread use because it is supplied in vials containing fixed doses that may not be appropriate for all patients–resulting…
COVID-19 fattens up our body’s cells to fuel its viral takeover
RICHLAND, Wash.—The virus that causes COVID-19 undertakes a massive takeover of the body’s fat-processing system, creating cellular storehouses of fat that empower the virus to hijack the body’s molecular machinery and cause disease. After scientists discovered the important role of…
Common antiretroviral drug improves cognition in mouse model of Down syndrome
Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research…
Gene variants may affect length of survival in Parkinson’s patients, new study shows
Scientists from four institutes in Paris, including the prestigious Paris Brain Institute at the Sorbonne Université, studied the records of 2,037 Parkinson’s disease patients from their first hospital visit and believe the genetic variants may shed light in how fast…
Prostate cancer hijacks tumor cell biorhythm to evade hormone therapy
Hormone therapy is successful at keeping metastatic prostate cancer under control, but eventually the tumor cells become resistant to it. An unexpected potential solution has now emerged in medicines not designed to fight cancer, but to target proteins that regulate…
Ancient microbes may help us find extraterrestrial life forms
Using light-capturing proteins in living microbes, scientists have reconstructed what life was like for some of Earth’s earliest organisms. These efforts could help us recognize signs of life on other planets, whose atmospheres may more closely resemble our pre-oxygen planet….
Nitric-oxide accelerates germination in chickpea
The functional role of nitric oxide in flooding stress: Molecular oxygen is required for respiration in all aerobic organisms but oxygen levels are very low in some plant organs such as seeds, tubers and buds, where hypoxia is linked to…
A Breakthrough, First Cryo-EM Structure from India
Recently, scientists from NCCS, Pune have studied a protein with the help of Cryo-EM to gain its structural and functional insights. It is considered to be the first Cryo-EM based structure determination study, carried entirely in India. The study has been published…
